This Cajun Chicken Alfredo Orzo is a creamy and flavorful dish that’s perfect for dinner. With tender chicken and a bit of spice, it brings a fun twist to traditional pasta.
Honestly, the blend of Cajun spices and creamy sauce keeps me coming back for more. Plus, you can whip it up in just one pot—less mess, more yum! Who doesn’t love that? 😊
Key Ingredients & Substitutions
Chicken: Boneless, skinless chicken breasts are perfect here, as they cook quickly and stay tender. If you want, you can swap them for thighs for extra flavor or use shrimp for a seafood twist!
Cajun Seasoning: This dish shines with Cajun spice! If you don’t have it, you can make your own with paprika, garlic powder, onion powder, thyme, and cayenne pepper for heat.
Orzo Pasta: Orzo gives a nice texture but any small pasta like ditalini or even quinoa can be great alternatives. Just adjust cooking times accordingly.
Heavy Cream: For a lighter version, use half-and-half or whole milk. Coconut cream can work if you’re looking for a dairy-free option but will add a slight coconut taste.
Parmesan Cheese: While grated Parmesan adds a nice salty finish, you can use Pecorino Romano or nutritional yeast for a dairy-free approach.
How Do I Get the Chicken Perfectly Cooked?
Getting the chicken just right is key! Here’s how to ensure it’s juicy and flavorful:
- Make sure to cut the chicken into uniform pieces for even cooking.
- Coat the chicken evenly with Cajun seasoning. Let it sit for a few minutes to absorb the flavors.
- Heat the skillet over medium-high. This helps to sear the outside quickly while keeping the inside moist.
- Cook the chicken in batches if your skillet is small; overcrowding can lead to steaming instead of browning.
- Don’t forget to let the chicken rest briefly after cooking for juicier bites!
What’s the Best Way to Combine Everything for Creamy Sauce?
The creamy Alfredo sauce is the star of the show! Here’s how to create that perfect, creamy texture:
- After adding the heavy cream, gently heat it. This helps avoid curdling.
- Stir in the grated Parmesan cheese gradually—this ensures it melts smoothly into the sauce.
- If the sauce is too thick, just whisk in a splash of chicken broth until you reach your desired consistency.
- Combine everything before serving, letting the chicken mingle in the creamy goodness for a minute or two.
Enjoy making this delicious Cajun Chicken Alfredo Orzo that’s sure to please everyone at the table!

Cajun Chicken Alfredo Orzo
Ingredients You’ll Need:
For the Chicken:
- 1 lb boneless, skinless chicken breasts, cut into bite-sized pieces
- 2 tbsp Cajun seasoning
- 1 tbsp olive oil
For the Vegetables:
- 1 small onion, finely chopped
- 2 cloves garlic, minced
- 8 oz mushrooms, sliced
For the Pasta:
- 1 cup orzo pasta
- 2 cups chicken broth
For the Alfredo Sauce:
- 1 cup heavy cream
- 1/2 cup grated Parmesan cheese
- Salt and freshly ground black pepper, to taste
For Garnish:
- Fresh parsley, chopped
- Optional: 1 small tomato, chopped or halved
How Much Time Will You Need?
This delicious dish takes about 10 minutes to prepare and around 25 minutes to cook, giving you a total of roughly 35 minutes from start to finish. Perfect for a quick weeknight dinner!
Step-by-Step Instructions:
1. Season and Cook Chicken:
In a mixing bowl, toss the chicken pieces with Cajun seasoning until they are evenly coated. Heat the olive oil in a large skillet over medium-high heat. Add the seasoned chicken to the skillet and cook until it’s browned and cooked through, about 5-7 minutes. Once done, remove the chicken from the skillet and set it aside.
2. Sauté Vegetables:
In the same skillet, add the chopped onion and minced garlic. Sauté them for about 2-3 minutes until they are fragrant and soft. Then, add the sliced mushrooms to the skillet and continue to cook until they release their moisture and turn slightly brown.
3. Cook Orzo:
Stir in the orzo pasta and allow it to cook for 1-2 minutes, lightly toasting it. Then, pour in the chicken broth, bring the mixture to a boil, and reduce the heat to a simmer. Cover the skillet and let the orzo cook until it’s tender and most of the liquid is absorbed, about 10 minutes. Be sure to stir occasionally to prevent sticking.
4. Make Alfredo Sauce:
Add the heavy cream and grated Parmesan cheese to the skillet. Cook on low heat, stirring frequently until the sauce thickens slightly, which should take about 3-5 minutes. Taste and season with salt and pepper as needed.
5. Combine and Garnish:
Return the cooked Cajun chicken to the skillet and stir everything together. Let the mixture simmer for a minute or two to meld the flavors. If you’d like, toss in some chopped or halved tomatoes for an extra dash of color and flavor. Finally, sprinkle with freshly chopped parsley.
6. Serve:
Serve your Cajun Chicken Alfredo Orzo hot. You can add a little more grated Parmesan or parsley on top for an inviting finish. Enjoy this creamy and spicy dish that’s bursting with flavor!
Bon appétit! Enjoy this delightful Cajun Chicken Alfredo Orzo with your family and friends!
Can I Use Whole Wheat Orzo Instead?
Absolutely! Whole wheat orzo can be substituted in this recipe for a healthier option. Just be aware that it may take a minute or two longer to cook, so keep an eye on it while simmering.
What If I Don’t Have Cajun Seasoning?
No problem! If you don’t have Cajun seasoning, you can easily make your own blend using paprika, cayenne pepper, garlic powder, onion powder, and thyme. Adjust to your desired spice level!
Can I Make This Dish Vegetarian?
Definitely! For a vegetarian version, omit the chicken and replace it with your favorite protein like chickpeas or tofu. You can also add more vegetables like zucchini or bell peppers for added flavor.
How Do I Store Leftovers?
Store any leftovers in an airtight container in the fridge for up to 3 days. To reheat, warm it gently in a skillet over medium heat or in a microwave, adding a splash of chicken broth or cream to restore creaminess!
